Glucose Challenge in Pregnancy Could Predict Heart Disease

Researchers published in the current issue of the Canadian Medical Association Journal.
say that abnormal test results in those without gestational diabetes signals future heart risk,
A glucose challenge test given to pregnant women may also show if they have an increased risk of heart disease in the future. This finding is very important because doctors might be able to begin using current screening procedures for gestational diabetes to identify women who are at risk for developing heart disease later in life. Heart disease is the number-one killer of women in the United States and Canada.

While women with gestational diabetes -- a condition leading to temporarily high blood sugars during pregnancy -- have a higher risk of suffering with cardiovascular disease than those without, no one really knew if mild glucose intolerance in pregnancy is associated with heart disease.

Gestational diabetes is an important risk factor for future type 2 diabetes. Pregnant women are generally screened for gestational diabetes with a glucose challenge test during the second trimester. If the result is abnormal, it is followed by an oral glucose tolerance test to confirm the diagnosis.

In this study researchers examined data on 435,696 women in Ontario who gave birth between April 1994 and March 1998. All of the women were followed until March 31, 2008. The study excluded women who had preexisting diabetes.

"Women who had an abnormal glucose challenge test but then did not have gestational diabetes had an increased risk of future cardiovascular disease compared to the general population, but a lower risk than women who actually did have gestational diabetes," says co-author Dr. Baiju Shah, of the Institute for Clinical and Evaluative Sciences in Toronto.

HealthDay News
Aug. 24