Pepppermint Interferes with Statin Cholesterol Drugs

Joe Graedon is a pharmacologist and Teresa Graedon is an expert in medical anthropology and nutrition. They educate their audience at Joe says that you should not eat peppermints while taking a cholesterol-lowering medication.

Mint leaves
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He says that mint is somewhat similar to grapefruit in its effect on certain statin drugs. One study revealed that peppermint oil increases blood levels of felodipine (Plendil), which is used as a model for this type of drug interaction (Clinical Pharmacology and Therapeutics, September 2002).

Based on this research, one might anticipate that certain cholesterol-lowering drugs such as atorvastatin (Lipitor), lovastatin (Mevacor) and simvastatin (Zocor) also might be affected by peppermint oil. Crestor is one unaffected by this interaction, so that drug poses no worry.

Menthol also appears to have a similar effect. Someone consuming a lot of cough drops might need to be aware of this potential drug interaction.

Joe Graedon, Teresa Graedon
The People's Pharmacy
September 20, 2009